FACTS ABOUT LIMITED EDITION EXCLUSIVE LSD CRYSTAL) REVEALED

While in the LSD-sure crystal construction, the facet chain of the lid residue L209EL2 types intensive hydrophobic contacts with both LSD and surrounding residues in TMs III, IV, and V (Determine 4C). Once the lid moved aside to expose the binding pocket in simulation, several of such contacts broke. We Hence hypothesized that L209EL2 functions bei